discoidin receptor tyrosine kinase

Cat No.	Product Name	Synonyms	Targets
T3455	Merestinib	LY2801653	Discoidin Domain Receptor (DDR) , FLT , c-Met/HGFR , ROS , ROS Kinase
	Merestinib (LY2801653) is an orally available, small molecule inhibitor of the proto-oncogene c-Met (Ki: 2 nM) with potential antineoplastic activity. Merestinib electively binds to c-Met, thereby inhibiting c-Met phosph...
T4349	Sitravatinib	MG516,MGCD516	Discoidin Domain Receptor (DDR) , VEGFR , FLT , Trk receptor , TAM Receptor , c-Kit , Ephrin Receptor
	Sitravatinib (MGCD516) (MGCD516) is an inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, including c-Met, c-Kit, PDGFRα/β, PDGFR, and Axl.
T9659	LCB 03-0110	3-(2-(3-(Morpholinomethyl)phenyl)thieno[3,2-b]pyridin-7-ylamino)phenol	Discoidin Domain Receptor (DDR)
	LCB 03-0110 (3-(2-(3-(Morpholinomethyl)phenyl)thieno[3,2-b]pyridin-7-ylamino)phenol) is a potent inhibitor of discoidin domain receptor family tyrosine kinases and strongly inhibits several tyrosine kinases, including th...		Discoidin Domain Receptor (DDR)

Compounds

Merestinib

T3455

Synonym: LY2801653

Target: Discoidin Domain Receptor (DDR), FLT, c-Met/HGFR, ROS, ROS Kinase

Sitravatinib

T4349

Synonym: MG516,MGCD516

Target: Discoidin Domain Receptor (DDR), VEGFR, FLT, Trk receptor, TAM Receptor, c-Kit, Ephrin Receptor

LCB 03-0110

T9659

Synonym: 3-(2-(3-(Morpholinomethyl)phenyl)thieno[3,2-b]pyridin-7-ylamino)phenol

Target: Discoidin Domain Receptor (DDR)

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-01289	DDR1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	DDR1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.7 kDa and the accession number is A0A024RCQ1.
TMPY-03593	DDR2 Protein, Rhesus, Recombinant (His)	Rhesus	HEK293 Cells
	DDR2 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 44.1 kDa and the accession number is XP_001118219.1.
TMPY-03642	DDR2 Protein, Rhesus, Recombinant (hFc)	Rhesus	HEK293 Cells
	DDR2 Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 7.0 kDa and the accession number is XP_001118219.1.
TMPY-03098	DDR2 Protein, Rat, Recombinant (hFc)	Rat	HEK293 Cells
	DDR2 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 69.5 kDa and the accession number is B1WC09.
TMPY-03166	DDR2 Protein, Rat, Recombinant (His)	Rat	HEK293 Cells
	DDR2 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.9 kDa and the accession number is B1WC09.
TMPY-03313	DDR1 Protein, Rat, Recombinant (His)	Rat	HEK293 Cells
	DDR1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.3 kDa and the accession number is Q6MG19.
TMPY-03541	DDR1 Protein, Rat, Recombinant (hFc)	Rat	HEK293 Cells
	DDR1 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 70.9 kDa and the accession number is Q6MG19.
TMPY-01728	DDR2 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	DDR2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.88 kDa and the accession number is Q62371.
TMPY-02310	DDR1 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	DDR1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.4 kDa and the accession number is Q03146-1.
TMPY-04442	DDR1 Protein, Mouse, Recombinant (His & GST)	Mouse	Baculovirus Insect Cells
	DDR1 Protein, Mouse, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 75.8kDa and the accession number is Q03146-2.
TMPY-02506	DDR1 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	DDR1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 71 kDa and the accession number is Q03146-1.
TMPY-00773	DDR2 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	DDR2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 69.4 kDa and the accession number is Q16832.
TMPY-03625	DDR2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	DDR2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 44.1 kDa and the accession number is Q16832.
TMPY-04361	DDR2 Protein, Human, Recombinant (aa 422-855, His & GST)	Human	Baculovirus Insect Cells
	DDR2 Protein, Human, Recombinant (aa 422-855, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 77.1 kDa and the accession number is Q16832.
TMPH-01297	DDR1 Protein, Human, Recombinant (aa 21-417, His)	Human	HEK293 Cells
	Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival ...
TMPY-04382	DDR1 Protein, Human, Recombinant (aa 444-913, His & GST)	Human	Baculovirus Insect Cells
	DDR1 Protein, Human, Recombinant (aa 444-913, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 80 kDa and the accession number is Q08345-1.